HMM Summary Page: TIGR01147

FunctionV-type ATPase, G subunit
Trusted Cutoff56.95
Domain Trusted Cutoff56.95
Noise Cutoff50.45
Domain Noise Cutoff50.45
Isology Typeequivalog
EC Number3.6.3.14
HMM Length113
Mainrole CategoryEnergy metabolism
Subrole CategoryATP-proton motive force interconversion
Gene Ontology TermGO:0008553: hydrogen-exporting ATPase activity, phosphorylative mechanism molecular_function
GO:0015991: ATP hydrolysis coupled proton transport biological_process
GO:0016471: vacuolar proton-transporting V-type ATPase complex cellular_component
AuthorUjwal ML, Paulsen IT
Entry DateFeb 4 2001 5:40PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis model describes the vacuolar ATP synthase G subunit in eukaryotes and includes members from diverse groups e.g., fungi, plants, parasites etc. V-ATPases are multi-subunit enzymes composed of two functional domains: A transmembrane Vo domain and a peripheral catalytic domain V1. The G subunit is one of the subunits of the catalytic domain. V-ATPases are responsible for the acidification of endosomes and lysosomes, which are part of the central vacuolar system.