HMM Summary Page: TIGR01126

Functionprotein disulfide-isomerase domain
Trusted Cutoff107.20
Domain Trusted Cutoff107.20
Noise Cutoff81.45
Domain Noise Cutoff81.45
Isology Typeequivalog_domain
HMM Length105
Mainrole CategoryProtein fate
Subrole CategoryProtein folding and stabilization
Gene Ontology TermGO:0003756: protein disulfide isomerase activity molecular_function
GO:0006457: protein folding biological_process
AuthorHaft DH
Entry DateJan 16 2001 4:28PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM describes a domain of eukaryotic protein disulfide isomerases, generally found in two copies. The high cutoff for total score reflects the expectation of finding both copies. The domain is similar to thioredoxin but the redox-active disulfide region motif is APWCGHCK.