| Accession | TIGR01124 |
| Name | ilvA_2Cterm |
| Function | threonine ammonia-lyase, biosynthetic |
| Gene Symbol | ilvA |
| Trusted Cutoff | 411.30 |
| Domain Trusted Cutoff | 411.30 |
| Noise Cutoff | 325.50 |
| Domain Noise Cutoff | 325.50 |
| Isology Type | equivalog |
| EC Number | 4.3.1.19 |
| HMM Length | 499 |
| Mainrole Category | Amino acid biosynthesis |
| Subrole Category | Pyruvate family |
| Gene Ontology Term | GO:0004794: L-threonine ammonia-lyase activity molecular_function |
| | GO:0009097: isoleucine biosynthetic process biological_process |
| Author | Haft DH |
| Entry Date | Jan 15 2001 11:55AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This model describes a form of threonine ammonia-lyase, a pyridoxal-phosphate dependent enzyme, with two copies of the threonine dehydratase C-terminal domain (Pfam:PF00585). Members with known function participate in isoleucine biosynthesis and are inhibited by isoleucine.
Alternate name: threonine deaminase, threonine dehydratase.
Forms scoring between the trusted and noise cutoff tend to branch with this subgroup of threonine ammonia-lyase phylogenetically but have only a single copy of the C-terminal domain. |
| Genome Property | GenProp0162: isoleucine biosynthesis from threonine and pyruvate (HMM) |
