HMM Summary Page: TIGR01122

Functionbranched-chain amino acid aminotransferase
Gene SymbolilvE
Trusted Cutoff245.55
Domain Trusted Cutoff245.55
Noise Cutoff196.55
Domain Noise Cutoff196.55
Isology Typeequivalog
EC Number2.6.1.42
HMM Length298
Mainrole CategoryAmino acid biosynthesis
Subrole CategoryPyruvate family
Gene Ontology TermGO:0004084: branched-chain-amino-acid transaminase activity molecular_function
GO:0009082: branched chain family amino acid biosynthetic process biological_process
AuthorHaft DH
Entry DateJan 12 2001 2:54PM
Last ModifiedFeb 14 2011 3:27PM
CommentAmong the class IV aminotransferases are two phylogenetically separable groups of branched-chain amino acid aminotransferase (IlvE). The last common ancestor of the two lineages appears also to have given rise to a family of D-amino acid aminotransferases (DAAT). This model represents the IlvE family more strongly similar to the DAAT family.
Genome PropertyGenProp0162: isoleucine biosynthesis from threonine and pyruvate (HMM)
GenProp0163: valine biosynthesis from pyruvate (HMM)
GenProp0164: leucine biosynthesis from pyruvate and acetyl-CoA (HMM)