| Accession | TIGR01112 |
| Name | mtrD |
| Function | tetrahydromethanopterin S-methyltransferase, subunit D |
| Gene Symbol | mtrD |
| Trusted Cutoff | 126.85 |
| Domain Trusted Cutoff | 126.85 |
| Noise Cutoff | 101.85 |
| Domain Noise Cutoff | 101.85 |
| Isology Type | equivalog |
| EC Number | 2.1.1.86 |
| HMM Length | 223 |
| Mainrole Category | Transport and binding proteins |
| Subrole Category | Cations and iron carrying compounds |
| Gene Ontology Term | GO:0006810: transport biological_process |
| | GO:0019386: methanogenesis, from carbon dioxide biological_process |
| | GO:0030269: tetrahydromethanopterin S-methyltransferase activity molecular_function |
| Author | Ujwal ML, Haft DH, Paulsen IT |
| Entry Date | Jan 9 2001 4:11PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This model describes N5-methyltetrahydromethanopterin:
coenzyme M methyltransferase subunit D in methanogenic archaea. This methyltranferase is membrane-associated enzyme complex that uses methy-transfer reaction to drive sodium-ion pump. Archaea domain, have evolved energy-yielding pathways marked by one-carbon biochemistry featuring novel cofactors and enzymes. This transferase is involved in the transfer of 'methyl' group from N5-methyltetrahydromethanopterin to coenzyme M. In an accompanying reaction, methane is produced by two-electron reduction of the methyl moiety in methyl-coenzyme M by another enzyme methyl-coenzyme M reductase. |
| References | DR EXPERIMENTAL; SP|P80653; Methanosarcina mazei
RM 9559648
RT Cloning, sequencing and expression of the genes encoding the sodium translocating N5-methyltetrahydromethanopterin: coenzyme M methyltransferase of the methylotrophic archaeon Methanosarcina mazei Go1.
RA Lienard T, Gottschalk G.
RL FEBS Lett 1998 Mar 27;425(2):204-8
DR HAMAP; MF_01097; 8 of 8 |
| Genome Property | GenProp0288: tetrahydromethanopterin S-methyltransferase complex (HMM) |
| | GenProp0722: methanogenesis marker set (HMM) |
