HMM Summary Page: TIGR01081

FunctionUDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase
Gene Symbolmpl
Trusted Cutoff388.70
Domain Trusted Cutoff388.70
Noise Cutoff206.05
Domain Noise Cutoff206.05
Isology Typeequivalog
HMM Length448
Mainrole CategoryCell envelope
Subrole CategoryBiosynthesis and degradation of murein sacculus and peptidoglycan
Gene Ontology TermGO:0009252: peptidoglycan biosynthetic process biological_process
GO:0016881: acid-amino acid ligase activity molecular_function
AuthorHaft DH
Entry DateDec 19 2000 3:51PM
Last ModifiedFeb 14 2011 3:27PM
CommentAlternate name: murein tripeptide ligase
ReferencesDR SWISSPROT; P37773 DR EG12440; mpl RM 96404780 RT Identification of the mpl gene encoding UDP-N-acetylmuramate: L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase in Escherichia coli and its role in recycling of cell wall peptidoglycan. RA Mengin-Lecreulx D, van Heijenoort J, Park JT RL Bacteriol 1996 Sep;178(18):5347-52
Genome PropertyGenProp0158: peptidoglycan(murein) biosynthesis (HMM)