HMM Summary Page: TIGR01064

Functionpyruvate kinase
Gene Symbolpyk
Trusted Cutoff306.40
Domain Trusted Cutoff306.40
Noise Cutoff233.00
Domain Noise Cutoff233.00
Isology Typeequivalog
EC Number2.7.1.40
HMM Length476
Mainrole CategoryEnergy metabolism
Subrole CategoryGlycolysis/gluconeogenesis
Gene Ontology TermGO:0004743: pyruvate kinase activity molecular_function
GO:0005737: cytoplasm cellular_component
GO:0006096: glycolysis biological_process
AuthorHaft DH
Entry DateDec 4 2000 4:42PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars.
ReferencesRM 20179818 RT Pyruvate kinase of the hyperthermophilic crenarchaeote Thermoproteus tenax: physiological role and phylogenetic aspects. RA Schramm A, Siebers B, Tjaden B, Brinkmann H, Hensel R RL J Bacteriol 2000 Apr;182(7):2001-9
Genome PropertyGenProp0691: glycolysis (HMM)