HMM Summary Page: TIGR01040

FunctionV-type ATPase, B subunit
Trusted Cutoff804.65
Domain Trusted Cutoff804.65
Noise Cutoff710.35
Domain Noise Cutoff710.35
Isology Typeequivalog
EC Number3.6.3.14
HMM Length467
Mainrole CategoryTransport and binding proteins
Subrole CategoryCations and iron carrying compounds
Gene Ontology TermGO:0008553: hydrogen-exporting ATPase activity, phosphorylative mechanism molecular_function
GO:0015991: ATP hydrolysis coupled proton transport biological_process
GO:0016471: vacuolar proton-transporting V-type ATPase complex cellular_component
AuthorDurkin S
Entry DateNov 16 2000 4:06PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis models eukaryotic vacuolar (H+)-ATPase that is responsible for acidifying cellular compartments. This enzyme shares extensive sequence similarity with archaeal ATP synthase.
ReferencesRN [1] RM 99240666 RT Structure and Properties of the Vacuolar (H+)-ATPases. RA Forgac M; RL J Biol Chem 1999;274:12951-12954.