HMM Summary Page: TIGR01036

Functiondihydroorotate dehydrogenase (fumarate)
Gene SymbolpyrD
Trusted Cutoff200.00
Domain Trusted Cutoff200.00
Noise Cutoff200.00
Domain Noise Cutoff200.00
Isology Typeequivalog
EC Number1.3.98.1
HMM Length356
Mainrole CategoryPurines, pyrimidines, nucleosides, and nucleotides
Subrole CategoryPyrimidine ribonucleotide biosynthesis
Gene Ontology TermGO:0004158: dihydroorotate oxidase activity molecular_function
GO:0009220: pyrimidine ribonucleotide biosynthetic process biological_process
AuthorUjwal ML, Haft DH
Entry DateNov 15 2000 4:44PM
Last ModifiedFeb 14 2012 12:30PM
CommentThis model describes enzyme protein dihydroorotate dehydrogenase exclusively for subfamily 2. It includes members from bacteria, yeast, plants etc. The subfamilies 1 and 2 share extensive homology, particularly toward the C-terminus. This subfamily has a longer N-terminal region.
ReferencesDR COGS; COG0167 DR HAMAP; MF_00225; 260 of 263
Genome PropertyGenProp0187: pyrimidine (uridine-5'-phosphate) de novo biosynthesis (HMM)