HMM Summary Page: TIGR01026

FunctionATPase, FliI/YscN family
Trusted Cutoff379.50
Domain Trusted Cutoff379.50
Noise Cutoff247.55
Domain Noise Cutoff247.55
Isology Typesubfamily
EC Number3.6.3.14
HMM Length440
Mainrole CategoryEnergy metabolism
Subrole CategoryATP-proton motive force interconversion
AuthorDurkin S, Haft DH
Entry DateNov 8 2000 3:59PM
Last ModifiedAug 16 2012 9:07AM
CommentThis family of ATPases demonstrates extensive homology with ATP synthase F1, beta subunit. It is a mixture of members with two different protein functions. The first group is exemplified by Salmonella typhimurium FliI protein. It is needed for flagellar assembly, its ATPase activity is required for flagellation, and it may be involved in a specialized protein export pathway that proceeds without signal peptide cleavage. The second group of proteins function in the export of virulence proteins; exemplified by Yersinia sp. YscN protein an ATPase involved in the type III secretory pathway for the antihost Yops proteins.
ReferencesDR EXPERIMENTAL; EGAD|22700|23428; Salmonella typhimurium DR EXPERIMENTAL; EGAD|17899|18211; Yersinia sp.