HMM Summary Page: TIGR00996

Functionvirulence factor Mce family protein
Trusted Cutoff140.50
Domain Trusted Cutoff140.50
Noise Cutoff82.00
Domain Noise Cutoff82.00
Isology Typeparalog
HMM Length291
Mainrole CategoryCellular processes
Subrole CategoryPathogenesis
AuthorHaft DH
Entry DateOct 17 2000 2:27PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this paralogous family are found as six tandem homologous proteins in the same orientation per cassette, in four separate cassettes in Mycobacterium tuberculosis. The six members of each cassette represent six subfamilies. One subfamily includes the protein mce (mycobacterial cell entry), a virulence protein required for invasion of non-phagocytic cells.
ReferencesDR Interpro; IPR003399 DR PFAM; PF02470