HMM Summary Page: TIGR00993

Functionchloroplast protein import component Toc86/159, G and M domains
Trusted Cutoff660.70
Domain Trusted Cutoff660.70
Noise Cutoff204.75
Domain Noise Cutoff204.75
Isology Typesubfamily_domain
HMM Length763
Mainrole CategoryTransport and binding proteins
Subrole CategoryAmino acids, peptides and amines
AuthorHaft DH, Loftus BJ
Entry DateOct 10 2000 1:33PM
Last ModifiedFeb 14 2011 3:27PM
CommentThe long precursor of the 86K protein originally described is proposed to have three domains. The N-terminal A-domain is acidic, repetitive, weakly conserved, readily removed by proteolysis during chloroplast isolation, and not required for protein translocation. The other domains are designated G (GTPase) and M (membrane anchor); this family includes most of the G domain and all of M.
ReferencesRM 10712545 RT Initial binding of preproteins involving the Toc159 receptor can be bypassed during protein import into chloroplasts. RA Chen K, Chen X, Schnell DJ RL Plant Physiol 2000 Mar;122(3):813-22