HMM Summary Page: TIGR00978

Functionaspartate-semialdehyde dehydrogenase
Gene Symbolasd
Trusted Cutoff301.20
Domain Trusted Cutoff301.20
Noise Cutoff201.30
Domain Noise Cutoff201.30
Isology Typeequivalog
EC Number1.2.1.11
HMM Length342
Mainrole CategoryAmino acid biosynthesis
Subrole CategoryAspartate family
Gene Ontology TermGO:0004073: aspartate-semialdehyde dehydrogenase activity molecular_function
GO:0009089: lysine biosynthetic process via diaminopimelate biological_process
AuthorHaft DH
Entry DateOct 2 2000 11:24AM
Last ModifiedFeb 14 2011 3:27PM
CommentTwo closely related families of aspartate-semialdehyde dehydrogenase are found. They differ by a deep split in phylogenetic and percent identity trees and in gap patterns. Separate models are built for the two types in order to exclude the USG-1 protein, found in several species, which is specifically related to the Bacillus subtilis type of aspartate-semialdehyde dehydrogenase. Members of this type are found primarily in organisms that lack peptidoglycan.
ReferencesDR EXPERIMENTAL; EGAD|21487|22107; Leptospira borgpetersenii
Genome PropertyGenProp0160: aspartate semialdehyde biosynthesis from aspartate (HMM)