HMM Summary Page: TIGR00977
| Accession | TIGR00977 |
| Name | citramal_synth |
| Function | citramalate synthase |
| Gene Symbol | cimA |
| Trusted Cutoff | 450.00 |
| Domain Trusted Cutoff | 450.00 |
| Noise Cutoff | 325.00 |
| Domain Noise Cutoff | 325.00 |
| Isology Type | equivalog |
| EC Number | 2.3.1.182 |
| HMM Length | 526 |
| Mainrole Category | Unknown function |
| Subrole Category | General |
| Author | Haft DH |
| Entry Date | Sep 29 2000 4:43PM |
| Last Modified | Sep 15 2014 12:45PM |
| Comment | This model includes GSU1798 and is now known to represent citramalate synthase. Members are related to 2-isopropylmalate synthases and homocitrate synthases but phylogenetically distinct. The role is isoleucine biosynthesis, the first dedicated step. |
| References | RN [1] RM PMID:18245290 RT Elucidation of an alternate isoleucine biosynthesis pathway in Geobacter sulfurreducens. RA Risso C, Van Dien SJ, Orloff A, Lovley DR, Coppi MV RL J Bacteriol. 2008 Apr;190(7):2266-74. doi: 10.1128/JB.01841-07. |
| Genome Property | GenProp0193: lysine biosynthesis via alpha-aminoadipate (AAA pathway) (HMM) |