| Accession | TIGR00962 |
| Name | atpA |
| Function | ATP synthase F1, alpha subunit |
| Gene Symbol | atpA |
| Trusted Cutoff | 484.45 |
| Domain Trusted Cutoff | 484.45 |
| Noise Cutoff | 209.00 |
| Domain Noise Cutoff | 209.00 |
| Isology Type | equivalog |
| EC Number | 3.6.3.14 |
| HMM Length | 503 |
| Mainrole Category | Energy metabolism |
| Subrole Category | ATP-proton motive force interconversion |
| Gene Ontology Term | GO:0000275: mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) cellular_component |
| | GO:0015986: ATP synthesis coupled proton transport biological_process |
| | GO:0045261: proton-transporting ATP synthase complex, catalytic core F(1) cellular_component |
| | GO:0045262: plasma membrane proton-transporting ATP synthase complex, catalytic core F(1) cellular_component |
| | GO:0046933: hydrogen ion transporting ATP synthase activity, rotational mechanism molecular_function |
| Author | Durkin S, Haft DH |
| Entry Date | Sep 28 2000 11:51AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | The sequences of ATP synthase F1 alpha and beta subunits are related and both contain a nucleotide-binding site for ATP and ADP. They have a common amino terminal domain but vary at the C-terminus. The beta chain has catalytic activity, while the alpha chain is a regulatory subunit. The alpha-subunit contains a highly conserved adenine-specific noncatalytic nucleotide-binding domain. The conserved amino acid sequence is Gly-X-X-X-X-Gly-Lys. Proton translocating ATP synthase F1, alpha subunit is homologous to proton translocating ATP synthase archaeal/vacuolar(V1), B subunit. |
| References | DR EXPERIMENTAL; EGAD|19577|20051; E. coli
DR HAMAP; MF_01346; 698 of 715 |
| Genome Property | GenProp0128: F1/F0 ATPase (HMM) |
| | GenProp0800: bacterial core gene set, 1 or more per genome (HMM) |
