HMM Summary Page: TIGR00959

Functionsignal recognition particle protein
Gene Symbolffh
Trusted Cutoff473.20
Domain Trusted Cutoff473.20
Noise Cutoff453.65
Domain Noise Cutoff453.65
Isology Typeequivalog
HMM Length428
Mainrole CategoryProtein fate
Subrole CategoryProtein and peptide secretion and trafficking
Gene Ontology TermGO:0003924: GTPase activity molecular_function
GO:0005048: signal sequence binding molecular_function
GO:0009306: protein secretion biological_process
GO:0048501: signal recognition particle, plasma membrane targeting cellular_component
AuthorHaft DH, Loftus BJ
Entry DateSep 27 2000 3:39PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis model represents Ffh (Fifty-Four Homolog), the protein component that forms the bacterial (and organellar) signal recognition particle together with a 4.5S RNA. Ffh is a GTPase homologous to eukaryotic SRP54 and also to the GTPase FtsY (TIGR00064) that is the receptor for the signal recognition particle.
ReferencesDR URL; RM 11735405 RT Role of SRP RNA in the GTPase cycles of Ffh and FtsY. RA Peluso P, Shan SO, Nock S, Herschlag D, Walter P. RL Biochemistry 2001 Dec 18;40(50):15224-33
Genome PropertyGenProp0205: signal recognition system, bacterial (HMM)
GenProp0799: bacterial core gene set, exactly 1 per genome (HMM)