HMM Summary Page: TIGR00945

Functiontwin arginine-targeting protein translocase TatC
Gene SymboltatC
Trusted Cutoff132.70
Domain Trusted Cutoff132.70
Noise Cutoff92.55
Domain Noise Cutoff92.55
Isology Typeequivalog
HMM Length215
Mainrole CategoryProtein fate
Subrole CategoryProtein and peptide secretion and trafficking
Gene Ontology TermGO:0005887: integral to plasma membrane cellular_component
GO:0008565: protein transporter activity molecular_function
GO:0015628: protein secretion by the type II secretion system biological_process
AuthorLoftus BJ, Selengut J
Entry DateSep 20 2000 12:29PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis model represents the TatC translocase component of the Sec-independent protein translocation system. This system is responsible for translocation of folded proteins, often with bound cofactors across the periplasmic membrane [1]. A related model (TIGR01912) represents the archaeal clade of this family. TatC is often found in a gene cluster with the two other components of the system, TatA/E (TIGR01411) and TatB (TIGR01410). A model also exists for the Twin-arginine signal sequence (TIGR01409).
ReferencesRN [1] RM PMID: 12634324 RT Moving folded proteins across the bacterial cell membrane. RA Palmer T, Berks BC. RL Microbiology. 2003 Mar;149(Pt 3):547-56.
Genome PropertyGenProp0127: Tat (Sec-independent) protein export (HMM)