HMM Summary Page: TIGR00940

Functionmonovalent cation:proton antiporter
Gene SymbolCPA3
Trusted Cutoff920.45
Domain Trusted Cutoff920.45
Noise Cutoff834.40
Domain Noise Cutoff834.40
Isology Typesubfamily
HMM Length793
Mainrole CategoryTransport and binding proteins
Subrole CategoryCations and iron carrying compounds
Gene Ontology TermGO:0005451: monovalent cation:hydrogen antiporter activity molecular_function
GO:0015672: monovalent inorganic cation transport biological_process
GO:0015992: proton transport biological_process
AuthorLoftus BJ
Entry DateSep 19 2000 11:52AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis family of proteins constists of bacterial multicomponent K+:H+ and Na+:H+ antiporters. The best characterized systems are the PhaABCDEFG system of Rhizobium meliloti which functions in pH adaptation and as a K+ efflux system and the MnhABCDEFG system of Staphylococcus aureus which functions as a Na+:H+ antiporter.
ReferencesDR URL; DR Interpro; IPR003916 DR Interpro; IPR001750 DR Interpro; IPR001516 DR PFAM; PF00361 DR PFAM; PF00662