HMM Summary Page: TIGR00937

Functionchromate efflux transporter
Gene SymbolchrA
Trusted Cutoff171.70
Domain Trusted Cutoff171.70
Noise Cutoff119.50
Domain Noise Cutoff119.50
Isology Typesubfamily
HMM Length368
Mainrole CategoryTransport and binding proteins
Subrole CategoryAnions
Gene Ontology TermGO:0015109: chromate transmembrane transporter activity molecular_function
GO:0015703: chromate transport biological_process
AuthorLoftus BJ, Haft DH
Entry DateSep 18 2000 11:10AM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this family probably act as chromate transporters, and are found in Pseudomonas aeruginosa, Alcaligenes eutrophus, Vibrio cholerae, Bacillus subtilis, Ochrobactrum tritici, cyanobacteria and archaea. The protein reduces chromate accumulation and is essential for chromate resistance.
ReferencesDR Interpro; IPR003370 DR PFAM; PF02417 RN [1] RM PMID:18776016 RT The chromate-inducible chrBACF operon from the transposable element TnOtChr confers resistance to chromium(VI) and superoxide. RA Branco R, Chung AP, Johnston T, Gurel V, Morais P, Zhitkovich A RL J Bacteriol. 2008 Nov;190(21):6996-7003.