HMM Summary Page: TIGR00931

FunctionNa+/H+ antiporter NhaC
Gene SymbolnhaC
Trusted Cutoff370.00
Domain Trusted Cutoff370.00
Noise Cutoff250.00
Domain Noise Cutoff250.00
Isology Typeequivalog
HMM Length454
Mainrole CategoryTransport and binding proteins
Subrole CategoryCations and iron carrying compounds
Gene Ontology TermGO:0006814: sodium ion transport biological_process
GO:0006818: hydrogen transport biological_process
GO:0015385: sodium:hydrogen antiporter activity molecular_function
AuthorHaft DH, Loftus BJ
Entry DateSep 14 2000 4:01PM
Last ModifiedJan 27 2012 11:12AM
CommentA single member of the NhaC family, a protein from Bacillus firmus, has been functionally characterized.It is involved in pH homeostasis and sodium extrusion. Members of the NhaC family are found in both Gram-negative bacteria and Gram-positive bacteria. Intriguingly, archaeal homolog ArcD (just outside boundaries of family) has been identified as an arginine/ornithine antiporter.
ReferencesDR EXPERIMENTAL; SP|P27611; Bacillus firmus DR URL;