HMM Summary Page: TIGR00921

Functionefflux transporter, putative, hydrophobe/amphiphile efflux-3 (HAE3) family
Trusted Cutoff351.90
Domain Trusted Cutoff351.90
Noise Cutoff206.35
Domain Noise Cutoff206.35
Isology Typesubfamily
HMM Length733
Mainrole CategoryTransport and binding proteins
Subrole CategoryUnknown substrate
AuthorLoftus BJ, Haft DH
Entry DateSep 13 2000 11:37AM
Last ModifiedFeb 14 2011 3:27PM
CommentCharacterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea.
ReferencesDR URL; RM 10941792 RT The RND permease superfamily: an ancient, ubiquitous and diverse family that includes human disease and development proteins. RA Tseng TT, Gratwick KS, Kollman J, Park D, Nies DH, Goffeau A, Saier MH Jr. RL J Mol Microbiol Biotechnol. 1999 Aug;1(1):107-25.