HMM Summary Page: TIGR00915

FunctionRND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family
Trusted Cutoff940.35
Domain Trusted Cutoff940.35
Noise Cutoff456.65
Domain Noise Cutoff456.65
Isology Typesubfamily
HMM Length1050
Mainrole CategoryCellular processes
Subrole CategoryToxin production and resistance
Gene Ontology TermGO:0006810: transport biological_process
GO:0015562: efflux transmembrane transporter activity molecular_function
GO:0016021: integral to membrane cellular_component
AuthorLoftus BJ, Haft DH
Entry DateSep 12 2000 4:04PM
Last ModifiedFeb 14 2011 3:27PM
CommentProteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of Pfam HMM PF00873.
ReferencesDR URL; DR PFAM; PF00873; AcrB/AcrD/AcrF family