Accession | TIGR00915 |
Name | 2A0602 |
Function | RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family |
Trusted Cutoff | 940.35 |
Domain Trusted Cutoff | 940.35 |
Noise Cutoff | 456.65 |
Domain Noise Cutoff | 456.65 |
Isology Type | subfamily |
HMM Length | 1050 |
Mainrole Category | Cellular processes |
Subrole Category | Toxin production and resistance |
Gene Ontology Term | GO:0006810: transport biological_process |
| GO:0015562: efflux transmembrane transporter activity molecular_function |
| GO:0016021: integral to membrane cellular_component |
Author | Loftus BJ, Haft DH |
Entry Date | Sep 12 2000 4:04PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters.
This family is one of several subfamilies within the scope of Pfam HMM PF00873. |
References | DR URL; http://www-biology.ucsd.edu/~msaier/transport/2_A_6.html
DR PFAM; PF00873; AcrB/AcrD/AcrF family |