HMM Summary Page: TIGR00905

Functiontransporter, basic amino acid/polyamine antiporter (APA) family
Trusted Cutoff409.05
Domain Trusted Cutoff409.05
Noise Cutoff382.55
Domain Noise Cutoff382.55
Isology Typesubfamily
HMM Length473
Mainrole CategoryTransport and binding proteins
Subrole CategoryAmino acids, peptides and amines
Gene Ontology TermGO:0005275: amine transmembrane transporter activity molecular_function
GO:0005887: integral to plasma membrane cellular_component
GO:0015837: amine transport biological_process
AuthorLoftus BJ
Entry DateSep 12 2000 11:50AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis family includes several families of antiporters that, rather commonly, are encoded next to decarboxylases that convert one of the antiporter substrates into the other. This arrangement allows a cycle that can remove proteins from the cytoplasm and thereby protect against acidic conditions.