HMM Summary Page: TIGR00888

FunctionGMP synthase (glutamine-hydrolyzing), N-terminal domain
Gene SymbolguaA
Trusted Cutoff172.15
Domain Trusted Cutoff172.15
Noise Cutoff113.35
Domain Noise Cutoff113.35
Isology Typeequivalog_domain
EC Number6.3.5.2
HMM Length188
Mainrole CategoryPurines, pyrimidines, nucleosides, and nucleotides
Subrole CategoryPurine ribonucleotide biosynthesis
Gene Ontology TermGO:0003922: GMP synthase (glutamine-hydrolyzing) activity molecular_function
GO:0006177: GMP biosynthetic process biological_process
AuthorHaft DH
Entry DateSep 11 2000 3:22PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis protein of purine de novo biosynthesis is well-conserved. However, it appears to split into two separate polypeptide chains in most of the Archaea. This N-terminal region would be the smaller subunit.
ReferencesDR HAMAP; MF_01510; 33 of 34
Genome PropertyGenProp0696: xanthine utilization as a source of guanine-monophosphate (GMP) (HMM)
GenProp0697: guanine monophosphate (GMP) biosynthesis from inosine monophosphate (IMP) (HMM)