| Accession | TIGR00885 |
| Name | fucP |
| Function | L-fucose:H+ symporter permease |
| Gene Symbol | fucP |
| Trusted Cutoff | 280.40 |
| Domain Trusted Cutoff | 280.40 |
| Noise Cutoff | 264.85 |
| Domain Noise Cutoff | 264.85 |
| Isology Type | equivalog |
| HMM Length | 410 |
| Mainrole Category | Transport and binding proteins |
| Subrole Category | Carbohydrates, organic alcohols, and acids |
| Gene Ontology Term | GO:0005887: integral to plasma membrane cellular_component |
| | GO:0015535: fucose:hydrogen symporter activity molecular_function |
| | GO:0015756: fucose transport biological_process |
| Author | Ujwal ML, Loftus BJ, Paulsen IT |
| Entry Date | Sep 11 2000 2:59PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This family describes the L-fucose permease in bacteria. L-fucose(6-deoxy-L-galactose) is a monosaccharide found in glycoproteins and cell wall polysaccharides. L-fucose is used in bacteria through an inducible pathway mediated by atleast four enzymes: a permease, isomerase, kinase and an aldolase which are encoded by fucP, fucI, fucK, fucA respectively. The fuc genes belong to a regulon comprising of four linked operons: fucO, fucA, fucPIK and fucR. The positive regulator is encoded by fucR, whose protein responds to fuculose-1-phosphate, which acts as an effector. |
| References | RM 7783647
RT Topological analyses of the L-fucose-H+ symport protein, FucP, from Escherichia coli.
RA Gunn FJ, Tate CG, Sansom CE, Henderson PJ
RL Mol Microbiol 1995 Feb;15(4):771-83 |
| Genome Property | GenProp0458: fucose catabolism (HMM) |
