HMM Summary Page: TIGR00875

Functionfructose-6-phosphate aldolase
Gene Symbolfsa
Trusted Cutoff245.95
Domain Trusted Cutoff245.95
Noise Cutoff105.40
Domain Noise Cutoff105.40
Isology Typeequivalog
EC Number4.1.2.-
HMM Length213
Mainrole CategoryEnergy metabolism
Subrole CategoryPentose phosphate pathway
Gene Ontology TermGO:0016832: aldehyde-lyase activity molecular_function
AuthorHaft DH
Entry DateSep 8 2000 11:03AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM represents a family that includes the E. coli transaldolase homologs TalC and MipB, both shown to be fructose-6-phosphate aldolases rather than transaldolases as previously thought. It is related to but distinct from the transaldolase family of E. coli TalA and TalB. The member from Bacillus subtilis becomes phosphorylated during early stationary phase but not during exponential growth.
ReferencesRN [1] RM PMID:11120740 RT Fructose-6-phosphate aldolase is a novel class I aldolase from Escherichia coli and is related to a novel group of bacterial transaldolases. RA Schurmann M, Sprenger GA RL J Biol Chem. 2001 Apr 6;276(14):11055-61. DR HAMAP; MF_00496; 14 of 15