| Accession | TIGR00858 |
| Name | bioF |
| Function | 8-amino-7-oxononanoate synthase |
| Gene Symbol | bioF |
| Trusted Cutoff | 426.45 |
| Domain Trusted Cutoff | 426.45 |
| Noise Cutoff | 324.95 |
| Domain Noise Cutoff | 324.95 |
| Isology Type | equivalog |
| EC Number | 2.3.1.47 |
| HMM Length | 365 |
| Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
| Subrole Category | Biotin |
| Gene Ontology Term | GO:0008710: 8-amino-7-oxononanoate synthase activity molecular_function |
| | GO:0009102: biotin biosynthetic process biological_process |
| Author | Haft DH |
| Entry Date | Aug 10 2000 10:59AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | 7-keto-8-aminopelargonic acid synthetase is an alternate name.
This model represents 8-amino-7-oxononanoate synthase, the BioF protein of biotin biosynthesis. This model is based on a careful phylogenetic analysis to separate members of this family from 2-amino-3-ketobutyrate and other related pyridoxal phosphate-dependent enzymes. In several species, including Staphylococcus and Coxiella, a candidate 8-amino-7-oxononanoate synthase is confirmed by location in the midst of a biotin biosynthesis operon but scores below the trusted cutoff of this model. |
| Genome Property | GenProp0036: biotin biosynthesis (HMM) |
