HMM Summary Page: TIGR00856

Functiondihydroorotase, homodimeric type
Gene SymbolpyrC
Trusted Cutoff292.95
Domain Trusted Cutoff292.95
Noise Cutoff129.90
Domain Noise Cutoff129.90
Isology Typeequivalog
EC Number3.5.2.3
HMM Length341
Mainrole CategoryPurines, pyrimidines, nucleosides, and nucleotides
Subrole CategoryPyrimidine ribonucleotide biosynthesis
Gene Ontology TermGO:0004151: dihydroorotase activity molecular_function
GO:0009220: pyrimidine ribonucleotide biosynthetic process biological_process
AuthorHaft DH, Durkin S
Entry DateAug 3 2000 2:39PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis homodimeric form of dihydroorotase is less common in microbial genomes than a related dihydroorotase that appears in a complex with aspartyltranscarbamoylase or as a homologous domain in multifunctional proteins of pyrimidine biosynthesis in higher eukaryotes.
ReferencesDR ECOCYC; EG10806; pyrC DR PROSITE; PDOC00401; Dihydroorotase signatures DR HAMAP; MF_00219; 123 of 126
Genome PropertyGenProp0187: pyrimidine (uridine-5'-phosphate) de novo biosynthesis (HMM)