HMM Summary Page: TIGR00851

FunctionPTS system, mannitol-specific IIC component
Gene SymbolmtlA
Trusted Cutoff468.40
Domain Trusted Cutoff468.40
Noise Cutoff398.55
Domain Noise Cutoff398.55
Isology Typesubfamily
EC Number2.7.1.69
HMM Length340
Mainrole CategoryTransport and binding proteins
Subrole CategoryCarbohydrates, organic alcohols, and acids
AuthorPaulsen IT, Saier MH, Loftus BJ
Entry DateJul 25 2000 6:19PM
Last ModifiedFeb 14 2011 3:27PM
CommentBacterial PTS transporters transport and concomitantly phosphorylate their sugar substrates, and typically consist of multiple subunits or protein domains. The Fru family is a large and complex family which includes several sequenced fructose and mannitol-specific permeases as well as several putative PTS permeases of unknown specificities.The Fru family PTS systems typically have 3 domains, IIA, IIB and IIC, which may be found as 1 or more proteins. The fructose and mannitol transporters form separate phylogenetic clusters in this family. This family is specific for the IIC domain of the mannitol PTS transporters.
ReferencesSE ipaulsen DR URL; DR Interpro; IPR003352 PF PFAM; PF02378
Genome PropertyGenProp0119: PTS transport system (HMM)