HMM Summary Page: TIGR00847

Functioncytochrome oxidase maturation protein, cbb3-type
Gene SymbolccoS
Trusted Cutoff28.35
Domain Trusted Cutoff28.35
Noise Cutoff20.10
Domain Noise Cutoff20.10
Isology Typeequivalog
HMM Length51
Mainrole CategoryEnergy metabolism
Subrole CategoryElectron transport
Gene Ontology TermGO:0008535: respiratory chain complex IV assembly biological_process
AuthorHaft DH
Entry DateJul 25 2000 6:19PM
Last ModifiedFeb 14 2011 3:27PM
CommentCcoS from Rhodobacter capsulatus has been shown essential for incorporation of redox-active prosthetic groups (heme, Cu) into cytochrome cbb(3) oxidase. FixS of Bradyrhizobium japonicum appears to have the same function. Members of this family are found so far in organisms with a cbb3-type cytochrome oxidase, including Neisseria meningitidis, Helicobacter pylori, Campylobacter jejuni, Caulobacter crescentus, Bradyrhizobium japonicum, and Rhodobacter capsulatus.
ReferencesSE AL A2 hmmalign AL pima_manual RN [1] RM 20171584 RT Roles of the ccoGHIS gene products in the biogenesis of the cbb(3)-type cytochrome c oxidase. RA Koch HG, Winterstein C, Saribas AS, Alben JO, Daldal F RL J Mol Biol 2000 Mar 17;297(1):49-65 RN [2] RM 96241863 RT The Bradyrhizobium japonicum fixGHIS genes are required for the formation of the high-affinity cbb3-type cytochrome oxidase. RA Preisig O, Zufferey R, Hennecke H DR EXPERIMENTAL; EGAD|136707|145795; Rhodobacter capsulatus
Genome PropertyGenProp0483: cytochrome c oxidase, cbb3-type (HMM)