HMM Summary Page: TIGR00842

Functiontransporter, betaine/carnitine/choline transporter (BCCT) family
Trusted Cutoff407.55
Domain Trusted Cutoff407.55
Noise Cutoff340.30
Domain Noise Cutoff340.30
Isology Typesubfamily
HMM Length452
Mainrole CategoryTransport and binding proteins
Subrole CategoryOther
Gene Ontology TermGO:0015652: quaternary ammonium group:hydrogen symporter activity molecular_function
GO:0015697: quaternary ammonium group transport biological_process
AuthorPaulsen IT, Saier MH, Loftus BJ
Entry DateJul 25 2000 6:19PM
Last ModifiedFeb 14 2011 3:27PM
CommentThe Betaine/Carnitine/Choline Transporter (BCCT) Family (TC 2.A.15) Proteins of the BCCT family share the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]. The BCCT family includes transporters for carnitine, choline and glycine betaine. BCCT transporters have 12 putative TMS, and are energized by pmf-driven proton symport. Some of these permeases exhibit osmosensory and osmoregulatory properties inherent to their polypeptide chains.
ReferencesSE Ipaulsen AL clustalw_manual DR HAMAP; MF_01049; 20 of 21