HMM Summary Page: TIGR00836

Functionammonium transporter
Gene Symbolamt
Trusted Cutoff343.30
Domain Trusted Cutoff343.30
Noise Cutoff250.20
Domain Noise Cutoff250.20
Isology Typesubfamily
HMM Length406
Mainrole CategoryTransport and binding proteins
Subrole CategoryCations and iron carrying compounds
Gene Ontology TermGO:0008519: ammonium transmembrane transporter activity molecular_function
GO:0015696: ammonium transport biological_process
AuthorPaulsen IT, Saier MH, Loftus BJ
Entry DateJul 25 2000 6:19PM
Last ModifiedFeb 14 2011 3:27PM
CommentThe Ammonium Transporter (Amt) Family (TC 2.A.49) All functionally characterized members of the Amt family are ammonia or ammonium uptake transporters. Some, but not others, also transport methylammonium. The mechanism of energy coupling, if any, to methyl-NH2 or NH3 uptake by the AmtB protein of E. coli is not entirely clear. NH4+ uniport driven by the pmf, energy independent NH3 facilitation, and NH4+/K+ antiport have been proposed as possible transport mechanisms. In Corynebacterium glutamicum and Arabidopsis thaliana, uptake via the Amt1 homologues of AmtB has been reported to be driven by the pmf.
ReferencesA2 hmmalign SE Ipaulsen AL clustalw_manual