| Accession | TIGR00832 |
| Name | acr3 |
| Function | arsenical-resistance protein |
| Gene Symbol | arsB |
| Trusted Cutoff | 282.80 |
| Domain Trusted Cutoff | 282.80 |
| Noise Cutoff | 173.70 |
| Domain Noise Cutoff | 173.70 |
| Isology Type | equivalog |
| HMM Length | 327 |
| Mainrole Category | Cellular processes |
| Subrole Category | Detoxification |
| Gene Ontology Term | GO:0008490: arsenite secondary active transmembrane transporter activity molecular_function |
| | GO:0015700: arsenite transport biological_process |
| | GO:0046685: response to arsenic-containing substance biological_process |
| Author | Paulsen IT, Saier MH, Loftus BJ |
| Entry Date | Jul 25 2000 6:19PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | The Arsenical Resistance-3 (ACR3) Family (TC 2.A.59)
The first protein of the ACR3 family functionally characterized was the ACR3 protein of Saccharomyces cerevisiae. It is present in the yeast plasma membrane and pumps arsenite out of the cell in response to the pmf. Similar proteins are found in bacteria, often as part of a four gene operon with an regulatory protein ArsR, a protein of unknown function ArsH, and an arsenate reductase that converts arsenate to arsenite to facilitate transport. |
| Genome Property | GenProp0474: arsenical resistance system (HMM) |
