HMM Summary Page: TIGR00832

Functionarsenical-resistance protein
Gene SymbolarsB
Trusted Cutoff282.80
Domain Trusted Cutoff282.80
Noise Cutoff173.70
Domain Noise Cutoff173.70
Isology Typeequivalog
HMM Length327
Mainrole CategoryCellular processes
Subrole CategoryDetoxification
Gene Ontology TermGO:0008490: arsenite secondary active transmembrane transporter activity molecular_function
GO:0015700: arsenite transport biological_process
GO:0046685: response to arsenic-containing substance biological_process
AuthorPaulsen IT, Saier MH, Loftus BJ
Entry DateJul 25 2000 6:19PM
Last ModifiedFeb 14 2011 3:27PM
CommentThe Arsenical Resistance-3 (ACR3) Family (TC 2.A.59) The first protein of the ACR3 family functionally characterized was the ACR3 protein of Saccharomyces cerevisiae. It is present in the yeast plasma membrane and pumps arsenite out of the cell in response to the pmf. Similar proteins are found in bacteria, often as part of a four gene operon with an regulatory protein ArsR, a protein of unknown function ArsH, and an arsenate reductase that converts arsenate to arsenite to facilitate transport.
Genome PropertyGenProp0474: arsenical resistance system (HMM)