HMM Summary Page: TIGR00829

FunctionPTS system, Fru family, IIB component
Trusted Cutoff76.85
Domain Trusted Cutoff76.85
Noise Cutoff64.15
Domain Noise Cutoff64.15
Isology Typesubfamily_domain
EC Number2.7.1.69
HMM Length85
Mainrole CategoryTransport and binding proteins
Subrole CategoryCarbohydrates, organic alcohols, and acids
AuthorLoftus BJ
Entry DateJul 25 2000 6:19PM
Last ModifiedFeb 14 2011 3:27PM
CommentBacterial PTS transporters transport and concomitantly phosphorylate their sugar substrates, and typically consist of multiple subunits or protein domains. The Fru family is a large and complex family which includes several sequenced fructose and mannitol-specific permeases as well as several PTS components of unknown specificities. The fructose components of this family phosphorylate fructose on the 1-position. The Fru family PTS systems typically have 3 domains, IIA, IIB and IIC, which may be found as 1 or more proteins. The fructose and mannitol transporters form separate phylogenetic clusters in this family. This family is specific for the IIB domain of the fructose PTS transporters.
ReferencesSE ipaulsen DR URL;
Genome PropertyGenProp0119: PTS transport system (HMM)
GenProp0693: fructose utilization as fructose-1,6-bisphosphate (HMM)