HMM Summary Page: TIGR00819

FunctionAbgT transporter family
Gene SymbolydaH
Trusted Cutoff753.55
Domain Trusted Cutoff753.55
Noise Cutoff241.15
Domain Noise Cutoff241.15
Isology Typesubfamily
HMM Length521
Mainrole CategoryHypothetical proteins
Subrole CategoryConserved
AuthorPaulsen IT, Saier MH, Loftus BJ
Entry DateJul 7 2000 1:41PM
Last ModifiedFeb 14 2011 3:27PM
CommentThe p-Aminobenzoyl-glutamate transporter family includes two transporters, the AbgT (YdaH) protein of E. coli and MtrF of Neisseria gonorrhoea. AbgT is apparently cryptic in wild type cells, but when expressed on a high copy number plasmid, or when expressed at higher levels due to mutation, it allows utilization of p-aminobenzoyl-glutamate as a source of p-aminobenzoate for p-aminobenzoate auxotrophs. p-Aminobenzoate is a constituent of and a precursor for the biosynthesis of folic acid.
ReferencesSE Ipaulsen DR URL;