HMM Summary Page: TIGR00810

Functionpreprotein translocase, SecG subunit
Gene SymbolsecG
Trusted Cutoff30.85
Domain Trusted Cutoff30.85
Noise Cutoff27.80
Domain Noise Cutoff27.80
Isology Typeequivalog
HMM Length73
Mainrole CategoryProtein fate
Subrole CategoryProtein and peptide secretion and trafficking
Gene Ontology TermGO:0005887: integral to plasma membrane cellular_component
GO:0015450: P-P-bond-hydrolysis-driven protein transmembrane transporter activity molecular_function
GO:0043952: protein transport by the Sec complex biological_process
AuthorHaft DH
Entry DateJul 7 2000 1:41PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis family of proteins forms a complex with SecY and SecE. SecA then recruits the SecYEG complex to form an active protein translocation channel.
ReferencesRN [1] RM PMID:10698927 RT SecYEG assembles into a tetramer to form the active protein translocation channel. RA Manting EH, van Der Does C, Remigy H, Engel A, Driessen AJ RL EMBO J. 2000 Mar 1;19(5):852-61. RN [2] RM PMID:10074070 RT Functional identification of the product of the Bacillus subtilis yvaL gene as a SecG homologue. RA van Wely KH, Swaving J, Broekhuizen CP, Rose M, Quax WJ, Driessen AJ RL J Bacteriol. 1999 Mar;181(6):1786-92. RN [3] RM PMID:10954595 RT Re-annotating the Mycoplasma pneumoniae genome sequence: adding value, function and reading frames. RA Dandekar T, Huynen M, Regula JT, Ueberle B, Zimmermann CU, Andrade MA, Doerks T, Sanchez-Pulido L, Snel B, Suyama M, Yuan YP, Herrmann R, Bork P RL Nucleic Acids Res. 2000 Sep 1;28(17):3278-88.
Genome PropertyGenProp0209: Sec system preprotein translocase (HMM)
GenProp0799: bacterial core gene set, exactly 1 per genome (HMM)