HMM Summary Page: TIGR00802

Functiontransition metal uptake transporter, Ni2+-Co2+ transporter (NiCoT) family
Trusted Cutoff333.05
Domain Trusted Cutoff333.05
Noise Cutoff96.30
Domain Noise Cutoff96.30
Isology Typesubfamily
HMM Length281
Mainrole CategoryTransport and binding proteins
Subrole CategoryCations and iron carrying compounds
Gene Ontology TermGO:0000041: transition metal ion transport biological_process
GO:0005887: integral to plasma membrane cellular_component
GO:0046915: transition metal ion transmembrane transporter activity molecular_function
AuthorPaulsen IT, Saier MH, Loftus BJ
Entry DateJul 7 2000 1:40PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis family is found in both Gram-negative and Gram-positive bacteria. The functionally characterized members of the family catalyze uptake of either Ni2+ or Co2+ in a proton motive force-dependent process. Topological analyses with the HoxN Ni2+ transporter of Ralstonia eutropha (Alcaligenes eutrophus) suggest that it possesses 8 TMSs with its N- and C-termini in the cytoplasm.
ReferencesSE Ipaulsen DR URL;
Genome PropertyGenProp0051: urease (HMM)
GenProp0177: nickel-dependent hydrogenase (HMM)