| Accession | TIGR00802 |
| Name | nico |
| Function | transition metal uptake transporter, Ni2+-Co2+ transporter (NiCoT) family |
| Trusted Cutoff | 333.05 |
| Domain Trusted Cutoff | 333.05 |
| Noise Cutoff | 96.30 |
| Domain Noise Cutoff | 96.30 |
| Isology Type | subfamily |
| HMM Length | 281 |
| Mainrole Category | Transport and binding proteins |
| Subrole Category | Cations and iron carrying compounds |
| Gene Ontology Term | GO:0000041: transition metal ion transport biological_process |
| | GO:0005887: integral to plasma membrane cellular_component |
| | GO:0046915: transition metal ion transmembrane transporter activity molecular_function |
| Author | Paulsen IT, Saier MH, Loftus BJ |
| Entry Date | Jul 7 2000 1:40PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This family is found in both Gram-negative and Gram-positive bacteria. The functionally characterized members of the family catalyze uptake of either Ni2+ or Co2+ in a proton motive force-dependent process. Topological analyses with the HoxN Ni2+ transporter of Ralstonia eutropha (Alcaligenes eutrophus) suggest that it possesses 8 TMSs with its N- and C-termini in the cytoplasm. |
| References | SE Ipaulsen
DR URL;
http://www-biology.ucsd.edu/~msaier/transport/2_A_52.html |
| Genome Property | GenProp0051: urease (HMM) |
| | GenProp0177: nickel-dependent hydrogenase (HMM) |
