HMM Summary Page: TIGR00800

FunctionNCS1 nucleoside transporter family
Gene Symbolncs1
Trusted Cutoff353.10
Domain Trusted Cutoff353.10
Noise Cutoff113.20
Domain Noise Cutoff113.20
Isology Typesubfamily
HMM Length447
Mainrole CategoryTransport and binding proteins
Subrole CategoryNucleosides, purines and pyrimidines
AuthorPaulsen IT, Saier MH, Loftus BJ
Entry DateJul 7 2000 1:40PM
Last ModifiedFeb 14 2011 3:27PM
CommentThe Nucleobase:Cation Symporter-1 (NCS1) Family (TC 2.A.39) The NCS1 family consists of bacterial and yeast transporters for nucleobases including purines and pyrimidines. Members of this family possess twelve putative transmembrane a-helical spanners (TMSs). At least some of them have been shown to function in uptake by substrate:H+ symport mechanism.
ReferencesA2 hmmalign SE Ipaulsen AL clustalw_manual
Genome PropertyGenProp0686: allantoin catabolism to glyoxalate and urea (HMM-CLUST)
GenProp0687: allantoin catabolism to oxamate and carbamoyl-phosphate (HMM-CLUST)