| Accession | TIGR00786 |
| Name | dctM |
| Function | TRAP transporter, DctM subunit |
| Trusted Cutoff | 268.45 |
| Domain Trusted Cutoff | 268.45 |
| Noise Cutoff | 131.85 |
| Domain Noise Cutoff | 131.85 |
| Isology Type | subfamily |
| HMM Length | 405 |
| Mainrole Category | Transport and binding proteins |
| Subrole Category | Carbohydrates, organic alcohols, and acids |
| Gene Ontology Term | GO:0005887: integral to plasma membrane cellular_component |
| | GO:0015556: C4-dicarboxylate transmembrane transporter activity molecular_function |
| | GO:0015740: C4-dicarboxylate transport biological_process |
| | GO:0031317: tripartite ATP-independent periplasmic transporter complex cellular_component |
| Author | Paulsen IT, Saier MH, Loftus BJ |
| Entry Date | Jul 7 2000 1:40PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | The Tripartite ATP-independent Periplasmic Transporter (TRAP-T) Family (TC 2.A.56)- DctM subunit TRAP-T family permeases generally consist of three components, and these systems have so far been found in Gram-negative bacteria, Gram-postive bacteria and archaea. Only one member of the family has been both sequenced and functionally characterized. This system is the DctPQM system of Rhodobacter capsulatus (Forward et al., 1997). DctP is a periplasmic dicarboxylate (malate, fumarate, succinate) binding receptor that is biochemically well-characterized. DctQ is an integral cytoplasmic membrane protein with 4 putative transmembrane a-helical spanners (TMSs). DctM is a second integral cytoplasmic membrane protein with 12 putative TMSs. These proteins have been shown to be both necessary and sufficient for the proton motive
force-dependent uptake of dicarboxylates into R. capsulatus. |
| References | A2 hmmalign
SE Ipaulsen
AL clustalw_manual |
| Genome Property | GenProp0176: TRAP-T (tripartite ATP-independent periplasmic transporters) family transporters (HMM) |
| | GenProp0714: galactarate utilization via tartronate semi-aldehyde (HMM-CLUST) |
| | GenProp0714: galactarate utilization via tartronate semi-aldehyde (HMM-CLUST) |
| | GenProp0714: galactarate utilization via tartronate semi-aldehyde (MANUAL) |
