HMM Summary Page: TIGR00775

FunctionNa+/H+ antiporter, NhaD family
Trusted Cutoff577.10
Domain Trusted Cutoff577.10
Noise Cutoff409.25
Domain Noise Cutoff409.25
Isology Typesubfamily
HMM Length420
Mainrole CategoryTransport and binding proteins
Subrole CategoryCations and iron carrying compounds
Gene Ontology TermGO:0006814: sodium ion transport biological_process
GO:0006818: hydrogen transport biological_process
GO:0015385: sodium:hydrogen antiporter activity molecular_function
AuthorPaulsen IT, Saier MH, Loftus BJ
Entry DateJul 7 2000 1:40PM
Last ModifiedFeb 14 2011 3:27PM
CommentThese proteins are members of the NhaD Na+:H+ Antiporter (NhaD) Family (TC 2.A.62). A single member of the NhaD family has been characterized. This protein is the NhaD protein of Vibrio parahaemolyticus which has 12 GES predicted transmembrane regions. It has been shown to catalyze Na+/H+ antiport, but Li+ can also be a substrate.
ReferencesDR InterPro; IPR000676 SE Ipaulsen DR URL;