| Accession | TIGR00773 |
| Name | NhaA |
| Function | Na+/H+ antiporter NhaA |
| Gene Symbol | nhaA |
| Trusted Cutoff | 254.00 |
| Domain Trusted Cutoff | 254.00 |
| Noise Cutoff | 220.55 |
| Domain Noise Cutoff | 220.55 |
| Isology Type | equivalog |
| HMM Length | 374 |
| Mainrole Category | Transport and binding proteins |
| Subrole Category | Cations and iron carrying compounds |
| Gene Ontology Term | GO:0006814: sodium ion transport biological_process |
| | GO:0006818: hydrogen transport biological_process |
| | GO:0015385: sodium:hydrogen antiporter activity molecular_function |
| Author | Paulsen IT, Saier MH, Loftus BJ |
| Entry Date | Jul 7 2000 1:40PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | These proteins are members of the NhaA Na+:H+ Antiporter (NhaA) Family (TC. 2.A.33). The Escherichia coli NhaA protein probably functions in the regulation of the internal pH when the external pH is alkaline. It also uses the H+ gradient to expel Na+ from the cell. Its activity is highly pH dependent. Only the E. coli protein is functionally and structurally well characterized. |
| References | DR InterPro; IPR000676
SE Ipaulsen
DR URL; http://www-biology.ucsd.edu/~msaier/transport/2_A_33.html
DR HAMAP; MF_01844; 242 of 254 |
