HMM Summary Page: TIGR00764

Functionputative ATP-dependent protease
Trusted Cutoff516.60
Domain Trusted Cutoff516.60
Noise Cutoff121.00
Domain Noise Cutoff121.00
Isology Typeequivalog
HMM Length608
Mainrole CategoryProtein fate
Subrole CategoryDegradation of proteins, peptides, and glycopeptides
Gene Ontology TermGO:0004176: ATP-dependent peptidase activity molecular_function
GO:0006508: proteolysis biological_process
AuthorHaft DH
Entry DateJun 13 2000 5:57PM
Last ModifiedJul 18 2011 3:03PM
CommentThis HMM represents a set of proteins with extensive C-terminal homology to the ATP-dependent protease La, product of the lon gene of E. coli. The model is based on a seed alignment containing only archaeal members, but several bacterial proteins match the model well. Because several species, including Thermotoga maritima and Treponema pallidum, contain both a close homolog of the lon protease and nearly full-length homolog of the members of this family, we suggest there may also be a functional division between the two families. Members of this family from Pyrococcus horikoshii and Pyrococcus abyssi each contain a predicted intein.
ReferencesA2 hmmalign AL clustalw_manual DR URL;