HMM Summary Page: TIGR00763

Functionendopeptidase La
Gene Symbollon
Trusted Cutoff608.05
Domain Trusted Cutoff608.05
Noise Cutoff336.55
Domain Noise Cutoff336.55
Isology Typeequivalog
EC Number3.4.21.53
HMM Length795
Mainrole CategoryProtein fate
Subrole CategoryDegradation of proteins, peptides, and glycopeptides
Gene Ontology TermGO:0004252: serine-type endopeptidase activity molecular_function
GO:0006508: proteolysis biological_process
GO:0008846: endopeptidase La activity molecular_function
AuthorHaft DH
Entry DateJun 13 2000 5:57PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis protein, the ATP-dependent serine endopeptidase La, is induced by heat shock and other stresses in E. coli, B. subtilis, and other species. The yeast member, designated PIM1, is located in the mitochondrial matrix, required for mitochondrial function, and also induced by heat shock.
ReferencesA2 hmmalign AL clustalw_manual DR EXPERIMENTAL; EGAD|50657|YBL022C; Saccharomyces cerevisiae DR EXPERIMENTAL; EGAD|18728|EC0439; Escherichia coli DR EXPERIMENTAL; EGAD|5576|BS2814; Bacillus subtilis