| Accession | TIGR00760 |
| Name | araD |
| Function | L-ribulose-5-phosphate 4-epimerase |
| Gene Symbol | araD |
| Trusted Cutoff | 389.10 |
| Domain Trusted Cutoff | 389.10 |
| Noise Cutoff | 46.75 |
| Domain Noise Cutoff | 46.75 |
| Isology Type | equivalog |
| EC Number | 5.1.3.4 |
| HMM Length | 228 |
| Mainrole Category | Energy metabolism |
| Subrole Category | Sugars |
| Gene Ontology Term | GO:0008742: L-ribulose-phosphate 4-epimerase activity molecular_function |
| | GO:0019568: arabinose catabolic process biological_process |
| Author | Haft DH |
| Entry Date | Jun 13 2000 5:57PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | E. coli has two genes, sgaE and sgbE (YiaS), that are very close homologs of araD, the established L-ribulose-5-phosphate 4-epimerase of E. coli. SgbE, part of an operon for L-xylulose metabolism, also has L-ribulose-5-phosphate 4-epimerase activity; L-xylulose-5-phosphate may be converted into L-ribulose-5-phosphate by another product of that operon.
The homolog to this family from Mycobacterium smegmatis is flanked by putative araB and araA genes, consistent with it also being araD. |
| References | RN [1]
RM 97237725
RT The Bacillus subtilis L-arabinose (ara) operon: nucleotide sequence, genetic organization and expression.
RA Sa-Nogueira I, Nogueira TV, Soares S, de Lencastre H
RL Microbiology 1997 Mar;143 ( Pt 3):957-69
RN [2]
RM 10913097
RT Role of the yiaR and yiaS genes of Escherichia coli in metabolism of endogenously formed L-xylulose.
RA Ibanez E, Gimenez R, Pedraza T, Baldoma L, Aguilar J, Badia J.
RL J Bacteriol. 2000 Aug;182(16):4625-7.
DR EXPERIMENTAL; GB|AAA27025.1; Salmonella typhimurium
DR EXPERIMENTAL; SP|P08203; Escherichia coli
DR EXPERIMENTAL; SP|P94525; Bacillus subtilis |
