HMM Summary Page: TIGR00760

FunctionL-ribulose-5-phosphate 4-epimerase
Gene SymbolaraD
Trusted Cutoff389.10
Domain Trusted Cutoff389.10
Noise Cutoff46.75
Domain Noise Cutoff46.75
Isology Typeequivalog
EC Number5.1.3.4
HMM Length228
Mainrole CategoryEnergy metabolism
Subrole CategorySugars
Gene Ontology TermGO:0008742: L-ribulose-phosphate 4-epimerase activity molecular_function
GO:0019568: arabinose catabolic process biological_process
AuthorHaft DH
Entry DateJun 13 2000 5:57PM
Last ModifiedFeb 14 2011 3:27PM
CommentE. coli has two genes, sgaE and sgbE (YiaS), that are very close homologs of araD, the established L-ribulose-5-phosphate 4-epimerase of E. coli. SgbE, part of an operon for L-xylulose metabolism, also has L-ribulose-5-phosphate 4-epimerase activity; L-xylulose-5-phosphate may be converted into L-ribulose-5-phosphate by another product of that operon. The homolog to this family from Mycobacterium smegmatis is flanked by putative araB and araA genes, consistent with it also being araD.
ReferencesRN [1] RM 97237725 RT The Bacillus subtilis L-arabinose (ara) operon: nucleotide sequence, genetic organization and expression. RA Sa-Nogueira I, Nogueira TV, Soares S, de Lencastre H RL Microbiology 1997 Mar;143 ( Pt 3):957-69 RN [2] RM 10913097 RT Role of the yiaR and yiaS genes of Escherichia coli in metabolism of endogenously formed L-xylulose. RA Ibanez E, Gimenez R, Pedraza T, Baldoma L, Aguilar J, Badia J. RL J Bacteriol. 2000 Aug;182(16):4625-7. DR EXPERIMENTAL; GB|AAA27025.1; Salmonella typhimurium DR EXPERIMENTAL; SP|P08203; Escherichia coli DR EXPERIMENTAL; SP|P94525; Bacillus subtilis