HMM Summary Page: TIGR00757

Functionribonuclease, Rne/Rng family
Trusted Cutoff325.95
Domain Trusted Cutoff325.95
Noise Cutoff53.65
Domain Noise Cutoff53.65
Isology Typesubfamily_domain
EC Number3.1.4.-
HMM Length415
Mainrole CategoryTranscription
Subrole CategoryDegradation of RNA
Gene Ontology TermGO:0004540: ribonuclease activity molecular_function
GO:0006401: RNA catabolic process biological_process
AuthorHaft DH
Entry DateJun 13 2000 5:57PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis model describes ribonuclease G (formerly CafA, cytoplasmic axial filament protein A), the N-terminal domain of ribonuclease E in which ribonuclease activity resides, and related proteins. In E. coli, both RNase E and RNase G have been shown to play a role in the maturation of the 5' end of 16S RNA. The C-terminal half of RNase E (excluded from the seed alignment for this model) lacks ribonuclease activity but participates in mRNA degradation by organizing the degradosome.
ReferencesA2 hmmalign AL clustalw