HMM Summary Page: TIGR00752

Functionouter membrane lipoprotein, Slp family
Trusted Cutoff88.45
Domain Trusted Cutoff88.45
Noise Cutoff74.75
Domain Noise Cutoff74.75
Isology Typesuperfamily
HMM Length182
Mainrole CategoryCell envelope
Subrole CategoryOther
AuthorHaft DH
Entry DateMar 2 2000 2:33PM
Last ModifiedFeb 14 2011 3:27PM
CommentSlp superfamily members are present in the Gram-negative gamma proteobacteria Escherichia coli, which also contains a close paralog, Haemophilus influenzae and Pasteurella multocida and Vibrio cholera. The known members of the family to date share a motif LX[GA]C near the N-terminus, which is compatible with the possibility that the protein is modified into a lipoprotein with Cys as the new N-terminus. Slp from Escherichia coli is known to be a lipoprotein of the outer membrane and to be expressed in response to carbon starvation.
ReferencesRM 94293775 RT Characterization of the carbon starvation-inducible and stationary phase-inducible gene slp encoding an outer membrane lipoprotein in Escherichia coli. RA Alexander DM, St John AC RL Mol Microbiol 1994 Mar;11(6):1059-71