HMM Summary Page: TIGR00752

AccessionTIGR00752
Nameslp
Functionouter membrane lipoprotein, Slp family
Trusted Cutoff88.45
Domain Trusted Cutoff88.45
Noise Cutoff74.75
Domain Noise Cutoff74.75
Isology Typesuperfamily
HMM Length182
Mainrole CategoryCell envelope
Subrole CategoryOther
AuthorHaft DH
Entry DateMar 2 2000 2:33PM
Last ModifiedFeb 14 2011 3:27PM
CommentSlp superfamily members are present in the Gram-negative gamma proteobacteria Escherichia coli, which also contains a close paralog, Haemophilus influenzae and Pasteurella multocida and Vibrio cholera. The known members of the family to date share a motif LX[GA]C near the N-terminus, which is compatible with the possibility that the protein is modified into a lipoprotein with Cys as the new N-terminus. Slp from Escherichia coli is known to be a lipoprotein of the outer membrane and to be expressed in response to carbon starvation.
ReferencesRM 94293775 RT Characterization of the carbon starvation-inducible and stationary phase-inducible gene slp encoding an outer membrane lipoprotein in Escherichia coli. RA Alexander DM, St John AC RL Mol Microbiol 1994 Mar;11(6):1059-71