HMM Summary Page: TIGR00751

Function1,4-dihydroxy-2-naphthoate octaprenyltransferase
Gene SymbolmenA
Trusted Cutoff102.15
Domain Trusted Cutoff102.15
Noise Cutoff88.15
Domain Noise Cutoff88.15
Isology Typeequivalog
EC Number2.5.1.74
HMM Length284
Mainrole CategoryBiosynthesis of cofactors, prosthetic groups, and carriers
Subrole CategoryMenaquinone and ubiquinone
Gene Ontology TermGO:0009234: menaquinone biosynthetic process biological_process
GO:0046428: 1,4-dihydroxy-2-naphthoate octaprenyltransferase activity molecular_function
AuthorLoftus BJ, Haft DH
Entry DateMar 2 2000 2:33PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis membrane-associated enzyme converts 1,4-dihydroxy-2-naphthoic acid (DHNA) to demethylmenaquinone, a step in menaquinone biosynthesis.
ReferencesA2 hmmalign SE clustalw RM 98241547 RT Menaquinone (vitamin K2) biosynthesis: localization and characterization of the menA gene from Escherichia coli. RA Suvarna K, Stevenson D, Meganathan R, Hudspeth ME RL J Bacteriol 1998 May;180(10):2782-7 DR EXPERIMENTAL; EGAD|22028|EC3930; Escherichia coli
Genome PropertyGenProp0058: menaquinone biosynthesis via SEPHCHC (HMM)