| Accession | TIGR00739 |
| Name | yajC |
| Function | preprotein translocase, YajC subunit |
| Gene Symbol | yajC |
| Trusted Cutoff | 44.20 |
| Domain Trusted Cutoff | 44.20 |
| Noise Cutoff | 31.35 |
| Domain Noise Cutoff | 31.35 |
| Isology Type | equivalog |
| HMM Length | 84 |
| Mainrole Category | Protein fate |
| Subrole Category | Protein and peptide secretion and trafficking |
| Gene Ontology Term | GO:0005887: integral to plasma membrane cellular_component |
| | GO:0009306: protein secretion biological_process |
| | GO:0015450: P-P-bond-hydrolysis-driven protein transmembrane transporter activity molecular_function |
| Author | Haft DH |
| Entry Date | Feb 22 2000 11:32AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | While this protein is part of the preprotein translocase in Escherichia coli, it is not essential for viability or protein secretion. The N-terminus region contains a predicted membrane-spanning region followed by a region consisting almost entirely of residues with charged (acidic, basic, or zwitterionic) side chains. This small protein is about 100 residues in length, and is restricted to bacteria; however, this protein is absent from some lineages, including spirochetes and Mycoplasmas. |
| References | RN [1]
RM 97449133
RT The SecDFyajC domain of preprotein translocase controls preprotein movement by regulating SecA membrane cycling.
RA Duong F, Wickner W
RL EMBO J 1997 Aug 15;16(16):4871-9
RN [2]
RM 99043892
RT Cloning and sequencing of yajC and secD homologs of Brucella abortus and demonstration of immune responses to YajC in mice vaccinated with B. abortus RB51.
RA Vemulapalli R, Duncan AJ, Boyle SM, Sriranganathan N, Toth TE, Schurig GG
RL Infect Immun 1998 Dec;66(12):5684-91 |
| Genome Property | GenProp0209: Sec system preprotein translocase (HMM) |
