HMM Summary Page: TIGR00734

FunctionhisA/hisF family protein
Trusted Cutoff179.85
Domain Trusted Cutoff179.85
Noise Cutoff88.45
Domain Noise Cutoff88.45
Isology Typehypoth_equivalog
HMM Length221
Mainrole CategoryUnknown function
Subrole CategoryGeneral
AuthorHaft DH
Entry DateFeb 22 2000 11:31AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM models a family of proteins found so far in three archaeal species: Methanobacterium thermoautotrophicum, Methanococcus jannaschii, and Archaeoglobus fulgidus. This protein is homologous to phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (HisA) and, with lower similarity, to the cyclase HisF, both of which are enzymes of histidine biosynthesis. Each species with this protein also encodes HisA. The function of this protein is unknown.
ReferencesA2 hmmalign