HMM Summary Page: TIGR00728

Functionoligopeptide transporter, OPT superfamily
Trusted Cutoff128.35
Domain Trusted Cutoff128.35
Noise Cutoff121.65
Domain Noise Cutoff121.65
Isology Typesuperfamily
HMM Length659
AuthorHaft DH
Entry DateFeb 22 2000 11:31AM
Last ModifiedMar 7 2012 12:47PM
CommentThis superfamily has two main branches. One branch contains a tetrapeptide transporter demonstrated experimentally in three different species of yeast. The other family contains EspB of Myxococcus xanthus, a protein required for normal rather than delayed sporulation after cellular aggregation; its role is unknown but is compatible with transport of a signalling molecule. Homology between the two branches of the superfamily is seen most easily at the ends of the protein. The central regions are poorly conserved within each branch and may not be homologous between branches.
ReferencesA2 hmmalign AL PSI-BLAST_manual RN [1] RM 98305694 RT Schizosaccharomyces pombe isp4 encodes a transporter representing a novel family of oligope RA Lubkowitz MA, Barnes D, Breslav M, Burchfield A, Naider F, Becker JM RL Mol Microbiol 1998 May;28(4):729-41 RN [2] RM 20032045 RT Sporulation timing in Myxococcus xanthus is controlled by the espAB locus. RA Cho K, Zusman DR RL Mol Microbiol 1999 Nov;34(4):714-25